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News From The Journal Of Clinical Investigation: March 8, 2010
Warning sign for potential anticancer approach One treatment being investigated as an adjuvant for anticancer immunotherapies is the use of molecules that trigger the proteins TLR7 and TLR8. For example, the TLR7 stimulant imiquimod is used for the treatment of skin cancer and metastatic melanoma...
2nd European Lung Cancer Conference
Rapid advances in drug development, genetics and multidisciplinary treatment have brought the field of oncology to a critical moment, says Dr. Rafael Rosell from the Catalan Institute of Oncology in Badalona, Spain, co-chair of the second European Lung Cancer Conference (ELCC), which will be held in Geneva, Switzerland from 28 April to 1 May 2010...
Prolonged Use Of HRT Increases Incidence Of Lung Cancer By About 50 Percent: New Study
Women aged 50 to 76 who take estrogen plus progestin may have an increased risk of lung cancer, according to a new study published in the pre-print online edition of the Journal of Clinical Oncology...
The Effects Of Patient Attitudes On Patient Outcomes
Research published in the March edition of the Journal of Thoracic Oncology (JTO) explored the importance of a patient's outlook as it relates to health behavior and health status. Researchers focused on lung cancer patients and discovered that those who exhibited an optimistic disposition experienced more favorable outcomes than those with a pessimistic disposition...
'Salvage' Therapy Just As Suitable For NSCLC Patients Over Age 70 As For Younger Patients
Research published in the March issue of the Journal of Thoracic Oncology sought to determine whether differences existed in tolerance and efficacy between patients age 70 and over and younger patients with non-small cell lung cancer (NSCLC) receiving salvage targeted therapy with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) or chemotherapy...
Synta Presents STA-9090 NSCLC Data At The IASLC 10th Annual Targeted Therapies Of The Treatment Of Lung Cancer Meeting
Synta Pharmaceuticals Corp. (NASDAQ: SNTA), a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that Dr. Geoffrey I...
Novelos Therapeutics Pivotal Phase 3 Lung Cancer Trial Does Not Meet The Primary Survival Endpoint
Novelos Therapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical company focused on the development of therapeutics to treat cancer and hepatitis, today announced that the primary endpoint of improvement in overall survival was not met in Novelos' pivotal Phase 3 trial in advanced non-small cell lung cancer (NSCLC) studying its lead product, NOV-002, in combination with first-line chemotherapy...
BSD Medical Reports Publication Of Chinese Study Using The BSD-2000 Hyperthermia System To Treat Lung Cancer
BSD Medical Corporation (NASDAQ: BSDM) (the "Company" or "BSD") announced that a study titled "BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer" has been published in the current issue of The Chinese Journal of Lung Cancer (February 2010;13(2):132-135) by Yang, Zhao, and Wang...
Lilly, Merck, And Pfizer Join Forces To Accelerate Research And Improve Treatment Of Lung And Gastric Cancers In Asia
Eli Lilly and Company, Merck (also known as Merck Sharp & Dohme (MSD) outside the USA and Canada), and Pfizer Inc. today announced the formation of the Asian Cancer Research Group, Inc., (ACRG), an independent, not-for-profit company established to accelerate research and ultimately improve treatment for patients affected with the most commonly-diagnosed cancers in Asia...
Merrimack Pharmaceuticals Initiates Enrollment In A Phase 1/2 Combination Study Of MM-121 And Tarceva(R) In Patients With Non-Small Cell Lung Cancer
Merrimack Pharmaceuticals, Inc. announced that the first patient has received an initial dose in a Phase 1/2 clinical study combining MM-121 with Tarceva® (erlotinib) in patients with non-small cell lung cancer (NSCLC). This is the first of multiple trials that Merrimack and sanofi-aventis expect to initiate in 2010 as part of a broad Phase 2 clinical development program for MM-121...
African-Americans' Attitudes About Lung Cancer May Hinder Prevention
A new survey has found that African-Americans are more likely than whites to hold mistaken and fatalistic beliefs about lung cancer, as well as being more reluctant to consult a doctor about possible symptoms of the disease, according to researchers from Dana-Farber Cancer Institute and their collaborators...
In The "Year Of The Lung," Utah Company Freshmedx Announces Breakthrough Lung Cancer Diagnostic
In celebration of World Cancer Day and the Year of the Lung, Freshmedx today announced that it has entered into multiple discussions for the international license of its Bioconductance Scanning Platform (BSP). The BSP is a medical device that can dramatically improve the accuracy of pre-surgical lung cancer diagnosis in a simple and painless 12-minute scan...
Erlotinib Found To Be Marginally Cost-Effective In Economic Analysis
Weighing both magnitude of survival benefit and expense, researchers found that the drug erlotinib, which was found to improve overall survival by 2 months in patients with advanced non-small cell lung cancer, is marginally cost-effective...
Significant Hazards Discovered In New Research On Secondhand Smoke
New research by the Oklahoma Tobacco Research Center (OTRC) shows that concentrations of secondhand tobacco smoke inhaled in smoking rooms of restaurants and bars are exceptionally high and hazardous to health...
Surgery Alone Offers Reasonable Overall Survival For Stage I SCLC
Research published in February's edition of the Journal of Thoracic Oncology investigates the utilization of surgery and the subsequent need for radiotherapy (RT) when treating stage I small cell lung cancer (SCLC)...
First Actuarial Analysis Shows Significant Mortality Reduction When Lung Cancer Diagnosed Early
The first ever actuarial analysis of lung cancer mortality, published in Population Health Management Journal, provides strong evidence that earlier detection could reduce the number of late stage lung cancer deaths by over 70,000 people each year in the US...
IDBS Biomarker Discovery And Validation Solution Helps Lung Genomics Research Consortium Manage And Analyze Phenotypic And Genomic Data
IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung diseases...
Benefits Of CyberKnife Radiosurgery For Lung Cancer Drive Continued Adoption
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that more than 12,000 courses of lung cancer treatment have been completed with CyberKnife radiosurgery. Usage of CyberKnife radiosurgery for lung cancer continues to grow, as illustrated by a 25 percent increase year over year in calendar year 2009...
The Canadian Lung Association Recognizes 2010 As The Year Of The Lung
2010: Year of the Lung is a global initiative instituted by the Forum of International Respiratory Societies (FIRS), a collaboration of the world's leading professional respiratory organizations. 2010: Year of the Lung aims to raise awareness of and advocate for lung health globally and at the country level to reduce lung disease morbidity and mortality.Learn more on The Year of the Lung website...
An Enzyme Can Rid Cells Of A Gene Believed To Be Responsible For A Wide Range Of Cancers
Dr Jorg Hartkamp and Dr Stefan Roberts have found that the protease HtrA2 can "clean" cells of the oncogene WT1, which is found at high levels in many leukaemias and solid cancers such as breast and lung cancer. Their work has given drug designers a new target which will allow them to develop treatments for all these cancers in which WT1 expression is elevated...
YM BioSciences Announces FDA Clearance For Two Ongoing Phase II Nimotuzumab Trials Into USA
YM BioSciences Inc. (NYSE YMI, TSX:YM), announced that the FDA has advised the Company that it may now enroll patients at US clinical sites into two ongoing randomized, double-blind Phase II trials of its lead product, nimotuzumab...
Medical Acoustics Receives FDA 510(k) Clearance Of Therapeutic Lung Flute(R)
Medical Acoustics LLC, a commercial-stage medical device company which employs acoustic technologies for diagnostic and therapeutic medical applications, today announced that it has received FDA 510(k) clearance of its Therapeutic Lung Flute®...
More Than $2 Million In NIH Grants To Barrow Researchers For Nicotine Studies
Four scientists at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center have been awarded more than $2.2 million from the National Institutes of Health (NIH) to research the effects of nicotine and develop new tobacco-related drug therapies. The grants will fund three separate research projects at the Phoenix-based institute in the next several years. Ronald J...
Quitting Smoking Doubles Chance Of Survival For Lung Cancer Patients
A study published on bmj.com today reports that people diagnosed with early stage lung cancer can double their chances of survival over five years if they stop smoking compared with those who continue to smoke. This is the first evaluation of several studies that assess the effects of continued smoking after diagnosis of lung cancer...
Grant Funds New System To Diagnose And Treat Lung Cancer On-The-Spot
Scientists at The Methodist Hospital Research Institute in Houston received a research grant from the Cancer Prevention Research Institute of Texas (CPRIT) today to develop the first molecular image guided system to diagnose and treat small-cell peripheral lung cancer in one sitting...
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