Irritable-Bowel Syndrome News From Medical News Today Latest Health News and Medical News posted throughout the day, every day.
Irritable Bowel Syndrome Patients Not More Likely To Get Colon Cancer
Patients with irritable bowel syndrome are at no greater risk of having polyps, colon cancer or inflammatory bowel diseases than healthy people undergoing colonoscopies, according to new research published in the American Journal of Gastroenterology. "Patients and doctors get nervous about the symptoms of irritable bowel syndrome (IBS)," says William D. Chey, M.D...
The Therapeutic Effect Of Worm-Derived Proteins On Experimental Colitis
Patients with inflammatory bowel disease (IBD) suffer from chronic inflammation of the gut leading to gastrointestinal motility alterations with symptoms such as abdominal pain, cramps and diarrhea that profoundly affect their quality of life...
Thiopurine Therapy For IBD Improves Quality Of Life
Patients with inflammatory bowel diseases (IBDs) such as Crohn's disease or ulcerative colitis do perceive a benefit from thiopurine treatment. A report in the open access journal BMC Gastroenterology has demonstrated improved health-related quality of life in 92 IBD patients...
Celiac Disease Genes Identified In Immune System
A UK-led international study has identified four types of genetic disturbance in the immune system that lead to celiac disease, bringing to 40 the total number of known inherited factors that increase a person's risk of developing the disease...
enGene Inc. To Present Research Data On EG-10 For Inflammatory Bowel Disease (IBD)
enGene Inc., a privately-held biotechnology company, announced that Dr. Eric Hsu, Sr. Director of Preclinical Research, is scheduled to present recent data on the use of enGene's proprietary technology to concentrate delivery of interleukin-10 (IL-10) to the colon for treating IBD at the Canadian Association of Gastroenterology (CAG) annual scientific conference in Toronto...
Behavioral Health Registry For Pediatric Inflammatory Bowel Disease To Be Created With NIH Grant
The National Institutes of Health has awarded a two-year development grant to researchers with Hasbro Children's Hospital and the Bradley Hasbro Children's Research Center to better understand the role behavioral health plays in pediatric inflammatory bowel disease (IBD), a condition that causes chronic and painful inflammation in the gastrointestinal tract...
Tioga Pharmaceuticals, Inc. Raises $18 Million To Fund Phase 3 Clinical Trial In Irritable Bowel Syndrome
Tioga Pharmaceuticals, Inc. today announced the closing of an $18 million equity financing. Current investors Forward Ventures, New Leaf Venture Partners and BB Biotech Ventures were joined by new investor Genesys Capital Partners. The proceeds will be used to fund a Phase 3 clinical trial for asimadoline for the treatment of patients with diarrhea predominant Irritable Bowel Syndrome (D-IBS)...
New Guideline Identifies Major Risk Factors In The Development Of Colorectal Cancer In Children And Adults With Inflammatory Bowel Disease
Certain patients with inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease of the colon, have an increased risk of developing colorectal cancer compared to individuals without IBD...
Non-Hospitalised Patients With Active Inflammatory Bowel Disease Are 16 Times More Likely To Suffer A Blood Clot Than The General Population
Non-hospitalised patients with active inflammatory bowel disease (IBD) are 16 times more likely to suffer a blood clot (venous thromboembolism) than the non-hospitalised general population. These results suggest that active IBD in ambulatory patients might be a far greater risk factor for venous thromboembolism than previously recognised, and these patients could be a target for prophylaxis...
Distinct Demographic Profiles Between Crohn's Disease And Ulcerative Colitis
Although inflammatory bowel disease (IBD) [comprising mainly Crohn's disease (CD) and ulcerative colitis (UC)] is thought to affect about 150 000 people in the United Kingdom, the prevalence of severe IBD is not known. Mortality following hospitalization for IBD is significant but little has been reported on long-term follow-up...
Walkerton Tragedy: 10 Years Of Research Leads To Breakthrough
Studies of the victims of the Walkerton, Ont. tainted drinking water tragedy have led researchers to discover DNA variations in genes that increase the risk of developing post-infectious irritable bowel syndrome (PI-IBS). The sheer scale of infection and the recording of the health of Walkerton's citizens gave a team of researchers a unique opportunity to study the origin of this disorder...
Sufferers Of Crohn's Disease May Benefit From Vitamin D Supplements
A new study has found that Vitamin D, readily available in supplements or cod liver oil, can counter the effects of Crohn's disease...
Bacterial Phylotype Alterations In Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common gastrointestinal functional disorder that can greatly affect the patient's well being. Multiple interacting mechanisms, including alterations in the intestinal microbiota, are suspected to lie behind IBS aetiology. A research article published on December 21, 2009 in the World Journal of Gastroenterology addresses this problem...
GSK Exercises Option To Progress Development Of ChemoCentryx's Traficet-EN For The Treatment Of Inflammatory Bowel Diseases
GlaxoSmithKline (GSK) and ChemoCentryx, Inc. announced that GSK has exercised its option to obtain an exclusive license for further development and worldwide commercialization of Traficet-EN(TM) (CCX282-B), a specific CCR9 antagonist with the potential to offer a new approach for the treatment of inflammatory bowel diseases, including Crohn's disease...
Irritable Bowel Syndrome Does Not Respond To St. John's Wort
A Mayo Clinic research study published in the January issue of the American Journal of Gastroenterology finds that St. John's wort is not an effective treatment for irritable bowel syndrome (IBS). While antidepressants are frequently used to treat IBS, to date, no study has examined the success of using the herbal supplement St. John's wort in treating IBS...
St. John's Wort Not Helpful Treatment For Irritable Bowel Syndrome
A Mayo Clinic research study published in the January issue of The American Journal of Gastroenterology finds that St. John's wort is not an effective treatment for irritable bowel syndrome (IBS). While antidepressants are frequently used to treat IBS, to date, no study has examined the success of using the herbal supplement St. John's wort in treating IBS...
Inflammatory Mediator Regulates Diarrhea In Inflammatory Bowel Disease
Researchers led by Dr. Terrence A. Barrett of Northwestern University Medical School in Chicago. Illinois have discovered that activation of NK-ГЋВєB, an inflammatory mediator, results in diarrhea in inflammatory bowel disease (IBD). These results are presented in the January 2010 issue of the American Journal of Pathology...
Breakthrough On Causes Of Inflammatory Bowel Disease
New research by the University of Adelaide could help explain why some people are more prone to Crohn's disease, ulcerative colitis and other autoimmune diseases. A critical imbalance of the regulatory cells required to control the immune system has been revealed among people suffering inflammatory bowel disease...
Urologic And Non-Urologic Unexplained Clinical Conditions Overlap
UroToday.com - Unexplained clinical conditions have been referred to by many names including functional somatic syndromes. They are characterized by a lack of clear physical or biological etiology, or inconsistent demonstration of laboratory abnormalities...
A Survey Into The Current Situation Of Britain's Irritable Bowel Syndrome
A survey into the current situation of Britain's Irritable Bowel Syndrome (IBS) sufferers has thrown up an unexpected and worrying finding about a condition that affects one in five people...
Largest Gene Study In Childhood IBD Finds 5 New Genes
In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease. A research team led by Hakon Hakonarson, M.D., Ph.D...
Lexicon Announces Positive Phase 2 Results Of LX1031 In Non-Constipating Irritable Bowel Syndrome
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) announced that the company's investigational new drug, LX1031, a tryptophan hydroxylase (TPH) inhibitor, demonstrated positive results in clinically important parameters for the treatment of non-constipating irritable bowel syndrome (IBS)...
Ironwood And Forest Announce Positive Linaclotide Results From Two Pivotal Phase 3 Trials In Patients With Chronic Constipation
Ironwood Pharmaceuticals, Inc. and Forest Laboratories, Inc. (NYSE: FRX) today announced positive top-line results from two Phase 3 clinical trials assessing the safety and efficacy of once-daily dosing of the investigational drug linaclotide in patients with chronic constipation (CC)...
New Tool To Accelerate Discovery Of Autoimmune Disease Mechanisms And Therapies
Currently, 5 - 8% of the U.S. population is afflicted with an autoimmune disease. Many of these are chronic and require life-long care. Moreover, different autoimmune diseases aggregate within a single family, suggesting they are caused by disruptions in common biological pathways...
Possible Link Between Inflammatory Bowel Disease Treatment And Non-Melanoma Skin Cancer
Findings from a new retrospective cohort study presented at the American College of Gastroenterology's 74th Annual Scientific meeting in San Diego indicate that patients with Inflammatory Bowel Disease (IBD), especially those receiving the thiopurine class of medications to treat IBD, may be at risk for developing non-melanoma skin cancer (NMSC). Dr...
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