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Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The Elderly
Purchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers...
Behavioral Problems In Childhood Double The Risk Of Chronic Widespread Pain In Adult Life
Bad behaviour in childhood is associated with long-term, chronic widespread pain in adult life, according to the findings of a study following nearly 20,000 people from birth in 1958 to the present day. Chronic widespread pain is a common complaint that can have a major adverse effect on quality of life, often requiring referral to a hospital specialist for investigation and treatment...
Nasty Or Nice? Two-Faced Testosterone
Is aggression always the best response to a challenge? Testosterone may not necessarily cause aggression but behavior can drive testosterone secretion...
What Is Hormone Replacement Therapy (HRT)? What Are The Benefits And Risks Of Hormone Replacement Therapy?
Hormone replacement therapy, commonly known as HRT is a treatment used to replace hormones that the body is no longer producing because of the menopause. The hormones that need replacing are estrogen and progesterone. The therapy is based on the notion that the treatment may prevent discomfort caused by diminished circulating estrogen and progesterone hormones...
Prolonged Use Of HRT Increases Incidence Of Lung Cancer By About 50 Percent: New Study
Women aged 50 to 76 who take estrogen plus progestin may have an increased risk of lung cancer, according to a new study published in the pre-print online edition of the Journal of Clinical Oncology...
Novo Nordisk Receives FDA Approval For Norditropin® FlexPro® For Growth Hormone Treatment
Novo Nordisk announced today that the U.S. Food and Drug Administration (FDA) has approved Norditropin® FlexPro® (somatropin [rDNA origin] injection), a pre-filled injection pen to be used by children and adults with growth hormone disorders. It will be available in the second quarter...
Researchers Discover A Direct Link Between The Hormone FGF21 And Brown Adipose Tissue
The blood glucose-lowering hormone FGF21 is also an activator of brown adipose tissue metabolism, according to the study featured on the cover of Cell Metabolism and directed by the lecturer Francesc Villarroya of the UB's Department of Biochemistry and Molecular Biology (Faculty of Biology), the Institute of Biomedicine, and the Biomedical Research Networking Centre in Physio...
Loyola Study Finds The Hormone Estrogen Inhibits A Protein That Causes Normal Cell Death In Breast Tumors
A new study is providing insight into how estrogen fuels many breast cancers, and researchers say the findings could lead to new cancer-fighting drugs. Researchers found that estrogen inhibits a protein called MLK3 that causes normal cell death. Blocking MLK3 leads to uncontrolled growth of cancer cells and resistance to chemotherapy...
Experts Call For Further Research Into The Relationship Between Insulin Therapy And Cancer
The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk...
Ghrelin Mitigates Liver Fibrosis In Animal Models; Regulates Human Fibrosis
Spanish researchers determined that rats treated with recombinant ghrelin displayed a reduction in liver fibrosis. Ghrelin, a stomach hormone, reduced the amount of fibrogenic cells by 25% in the treated rodents. Research further showed ghrelin prevented acute liver damage and reduced oxidative stress and inflammation in the animal models...
NPS Pharmaceuticals Announces Support For Rare Disease Day Observance
NPS Pharmaceuticals, a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, announced its support for the second annual U.S. Rare Disease Day observance on February 28. Rare Disease Day aims to call attention to the 7,000 rare diseases affecting people throughout the world, including nearly 30 million Americans...
Hormone Thought To Slow Aging Associated With Increased Risk Of Cancer Death
According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), older men with high levels of the hormone IGF-I (insulin-like growth factor 1) are at increased risk of cancer death, independent of age, lifestyle and cancer history...
Women's Hormone Replacement Therapy Linked To Cataracts; Smoking May Raise Uveitis Risk
Intriguing findings on hormone replacement therapy (HRT) and cataract risk, and on smoking and uveitis risk are reported in this month's Ophthalmology,the journal of the American Academy of Ophthalmology...
The Pig And Its Pancreas A Unique Model For A Common Disease
The incidence of diabetes is rising worldwide. Using genetic engineering techniques in pigs, scientists at Ludwig-Maximilians-Universität (LMU) in Munich have created a new model of this metabolic disorder, which recapitulates many features of the disease, and promises to contribute significantly to improvements in diagnosis and therapy...
Effective Prostate Cancer Treatment Discovery
Monash University biomedical scientists have identified a new way to treat castrate resistant cells in prostate cancer sufferers - the most common cancer in Australian men. For more than 60 years the main way to treat men with prostate cancer has involved removing the hormones that fuel growth of the cancer cells...
Researchers Gain Detailed Insight Into Failing Heart Cells Using New Nano Technique
Researchers have been able to see how heart failure affects the surface of an individual heart muscle cell in minute detail, using a new nanoscale scanning technique developed at Imperial College London...
Hormone Study Gives Scientists A Sense Of How Animals Bond
Scientists have pinpointed how a key hormone helps animals to recognise others by their smell. Researchers at the University of Edinburgh have shown that the hormone vasopressin helps the brain differentiate between familiar and new scents...
Effects Of Iodine Supplements On Maternal Thyroid Function Studied
Iodine is an essential element for synthesising thyroid hormones. A team of researchers from the Childhood and Environment Project (INMA) has studied the consequences of pregnant women consuming it in their diet and in supplements. The results suggest the need to evaluate their iodine nutritional status before systematically recommending taking it during pregnancy...
Lasofoxifene Helps Reduce Risk Of Bone Fractures, Breast Cancer, Heart Disease And Stroke
Low doses of the medication lasofoxifene can reduce the risk of vertebral and non-vertebral fractures, ER-positive breast cancer, coronary heart disease and stroke in postmenopausal women with osteoporosis. That's the finding of a new study in the latest issue of the New England Journal of Medicine...
Shire Provides Update On Biologics License Application (BLA) Filing For REPLAGAL(R) (agalsidase Alfa) With The U.S. Food And Drug Administration (FDA)
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces it has received Fast Track designation from the FDA for REPLAGAL(R) (agalsidase alfa), its enzyme replacement therapy for Fabry disease. Shire filed a BLA for REPLAGAL in December 2009...
Lab Research Targets 'Estrogen-Receptor Positive' Breast Cancer Cells; Identifies Key Protein
In a laboratory study published in the journal Cancer Research, Scott & White Healthcare anatomic pathologist Arundhati Rao, M.D. is a co-investigator looking at the ways in which estrogen can interfere with how chemotherapy does its job in destroying breast cancer cells. The most common type of breast cancer is "estrogen-receptor positive" breast cancer. Velusamy Rangasamy and Ajay Rana, Ph.D...
Hormone Changes During Menopause Increase Risk Of Heart Disease And Stroke
When women hear the word menopause, they often think about hot flashes, hormone shifts and mood swings. But what about heart disease? Studies show a woman's risk of heart disease intensifies drastically around the time of natural menopause, which for most women is around the age of 50...
National Leaders In The Scientific And Medical Communities Call For Improved Accuracy In Testosterone Testing
On February 18 and 19, The Endocrine Society, in conjunction with the CDC, brought together the nation's leading medical and scientific organizations to develop consensus recommendations for improving accuracy in testosterone assays. Testosterone assays are tests that measure testosterone levels which, in turn, are used to diagnose and treat patients with a number of disorders...
Male Cancer Survivors' Quality Of Life Affected By Testosterone Deficiency
A new study has found that many male cancer survivors who develop testosterone deficiency after receiving chemotherapy or radiation therapy have an impaired quality of life and reduced energy levels...
The Stress Of Poverty Discussed By Rockefeller Scientist At AAAS
The roots of many adult diseases sprout in poverty and other burdens on the socially disadvantaged. Rockefeller University's Bruce S. McEwen, a self-described molecular sociologist, talked about the effects such environmental stressors have on the brain and in turn other organ systems in a talk in San Diego at the 2010 meeting of the American Association for the Advancement of Science...
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