Cleft Palate News From Medical News Today Latest Health News and Medical News posted throughout the day, every day.
Growth Factor Gene Shown To Be A Key To Cleft Palate
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal...
Growth Factor Gene Shown To Be A Key To Cleft Palate
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal...
Pitt Researcher To Co-Direct National Consortium On Facial Birth Defects
Researchers at the University of Pittsburgh and the University of Iowa will lead a $9 million, five-year initiative to study the cause of facial birth defects. The FaceBase Consortium will create an encyclopedic database of how the faces of children develop and what goes wrong to cause malformations...
Progress Report On Cleft Palate Surgery In Developing Countries
Craniofacial surgeons around the world are striving toward a critical goal: making high-quality cleft palate and craniofacial reconstructive surgical services available to children in developing countries...
FaceBase Consortium Launched By NIDCR
Although about half of all birth defects involve the face and skull, scientists remain unclear about why most occur. To help families at risk for these conditions, what's needed is a comprehensive and systematic understanding of how the faces of healthy children develop and what goes awry to cause common malformations...
Titan Announces Award Of NIH Grant For Probuphine(R) Clinical Development
Titan Pharmaceuticals, Inc (Pink Sheets:TTNP) announced that the National Institutes of Health (NIH) has awarded a Research and Research Infrastructure Grand Opportunities grant to the company through the American Reinvestment and Recovery Act of 2009 (ARRA). The two year grant for Probuphine clinical development is expected to provide approximately $7...
PCE Exposure Increases Risk Of Birth Defects
Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water, published in BioMed Central's open access journal Environmental Health, found an increased risk of oral clefts and neural tube defects in their children...
PSivida Corp Reports Favorable 12-Month Interim Safety And Efficacy Results From Iluvienâ„¢ Human PK Study
pSivida Corp, a leading drug delivery company, reported the interim 12-month safety and efficacy results from the first human pharmacokinetic study (PK Study) of Iluvienâ„¢. The study is being conducted by the Company's licensing partner Alimera Sciences. Iluvien is an intravitreal insert being developed for the treatment of diabetic macular edema (DME)...
Bonn Scientists Discover Gene Locus Associated With Cleft Lip And Palate
Comparing 500,000 snippets of human DNA put scientists from the University of Bonn on the right track. A genetic variant on chromosome 8 occurs with significantly higher frequency in people with cleft lip and palate than in the control group. The results are to be published in the forthcoming issue of the journal Nature Genetics...
Increased Prevalence Of Left-Handedness In Children With Facial Development Disorder
A new study by physician researchers from Hasbro Children's Hospital and Children's Hospital Boston has identified an increased prevalence in left-handedness in children with a congenital disorder known as hemifacial microsomia (HFM). The study was published in the March 2009 edition of the Journal of Craniofacial Surgery. Overall, ten percent of the population is left-handed...
Scientists Discover Why Teeth Form In A Single Row And How Each Tooth Signals The Next To Start Growing
A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science. When completely understood, the genetic program described in the study may help guide efforts to re-grow missing teeth and prevent cleft palate, one of the most common birth defects...
Advancement In Tissue Engineering Promotes Oral Wound Healing
Oral tissue engineering for transplantation to aid wound healing in mouth (oral cavity) reconstruction has taken a significant step forward with a Netherlands-based research team's successful development of a gum tissue (gingival) substitute that can be used for reconstruction in the oral cavity. Their work was reported in the current issue of Cell Transplantation (17:10/11)...
Study Of Changes In MSX Gene Family Over 600 Million Years Leads To New Understanding Of Disease Patterns
The work of Forsyth scientist Peter Jezewski, DDS, Ph.D., has revealed that duplication and diversification of protein regions ('modules') within ancient master control genes is key to the understanding of certain birth disorders...
Oral Clefts And First Trimester Smoking Linked
Smoking during the first trimester of pregnancy is clearly linked with an increased risk of cleft lip in newborns. Genes that play a role in detoxification of cigarette smoke do not appear to be involved. This is shown in a new study published in the journal Epidemiology. Oral clefts are one of the most common birth defects...
Increased Risk Of Birth Defects Linked To Maternal Smoking
Babies whose mothers smoked during pregnancy were more than twice as likely to have a cleft palate or lip as those whose mothers didn't, according to research results released today. Although the study confirms earlier findings, it is unique because it did not rely on women's self-reported smoking habits during pregnancy...
Genetic Variant Plays Role In Cleft Lip
University of Iowa researchers and collaborators have found, in a previously identified gene, a variation that likely contributes to one in five cases of isolated cleft lip. It is the first time a genetic variant has been associated with cleft lip alone, rather than both cleft lip and palate...
Susceptibility To Cleft Palate Revealed By Genetic Profile
For the first time, researchers from the University of Pittsburgh School of Dental Medicine have identified a series of genetic mutations that appear to be linked to significant risk for cleft palate and other dental abnormalities...
Alternate Pathway That Leads To Palate Development
Researchers at the University Of Southern California School Of Dentistry have uncovered another clue behind the causes of cleft palate and the process that leads to palate formation. Cleft palate is one of the most common congenital birth defects, occurring in one out of every 700 live births. Clefts are more common in children of American Indian, Hispanic or Asian descent...
Alcohol Binges Early In Pregnancy Increase Risk Of Infant Oral Clefts
A new study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that pregnant women who binge drink early in their pregnancy increase the likelihood that their babies will be born with oral clefts...
California Legislature Takes Up Multiple Health Care Bills
"More than a dozen health bills are advancing through the [California] Legislature," some of which contain elements of a health care overhaul plan backed by Gov. Arnold Schwarzenegger (R) that passed the state Assembly but was rejected in the Senate earlier this year, the Los Angeles Times reports...
Research Findings Change The Way Doctors Perform Cleft Palate Surgery
Research by Dr. Damir Matic, a scientist with Lawson Health Research Institute in London, Ontario is changing the way cleft palate surgeries are performed throughout North America and around the world. Matic has been conducting research to determine the optimal time to close the gum tissue of cleft palate patients. His research suggests that it is best to wait until the child is older...
Gene For Branchio-Oculo-Facial Syndrome Discovered By Researchers
In a collaborative effort, researchers from Boston University School of Medicine (BUSM) have discovered that deletions or mutations within the TFAP2A gene (Activating Enhancer-Binding Protein) result in the distinctive clefting disorder Branchio-Oculo-Facial syndrome (BOFS)...
Keynoters, Symposia, Workshops Highlight Dental Research Meeting
Following is a summary of the keynote presentations, symposia, and workshops that will anchor the 37th Annual Meeting of the American Association for Dental Research, convening April 2 at the Hilton Anatole Hotel...
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